DMSO Potentiation Therapy

Posted On February 24, 2021 at 1:33 pm by / No Comments

DMSO Potentiation Therapy

DMSO (dimethylsulfoxide) is another molecule that can be used to carry toxins into cancer cells because of its high affinity for cancer cells. The following facts regarding DMSO are relevant:


  • DMSO, because of its great affinity for cancer cells, targets cancer cells in the presence of normal cells for reasons that are not fully understood.
  • DMSO binds chemically to certain kinds of chemotherapy drugs to form complexes.
  • The DMSO-drug complexes thus formed will draw the drug into the cancer cells.
  • The toxic chemotherapy drug in the complex is still able to kill the cancer cells, and, at much reduced dosage levels, toxicity and sideeffects are virtually non-existent.
  • On their own, the chemotherapy drugs are so toxic and non-selective that they kill far more normal cells than cancer cells, which is why toxic side-effects are such a problem with chemotherapy.
  • DMSO is especially valuable in brain cancer patients, but is also valuable in the treatment of other cancers. DMSO readily crosses the bloodbrain barrier.
  • DMSO is remarkably non-toxic. It has been used in doses of 2-4g/kg per day without noteworthy side-effects.
  • 5-10% DMSO solutions have been used as a carrier vehicle for a variety of drugs, including the usual chemotherapy drugs.
  • The first studies which demonstrated the potentiating effect of DMSO on drug action were done with the aid of a dye haematoxylin (Hauser and Hauser, Ibid.). The researchers were able to show that only cancer cells were coloured by the dye in the presence of DMSO, indicating that DMSO carried the dye, so to speak, into the cancer cells. This showed that DMSO specifically targeted the cancer cells.
  • A further great advantage of DMSO is that it readily crosses the bloodbrain barrier, thus making it possible to use drugs (including many chemotherapy drugs) in combination with DMSO to treat brain conditions that would have been impossible otherwise.
  • The DMSO effect has been demonstrated with other compounds such as hydrogen peroxide, cesium chloride, MSM and other products. It does not combine with all the chemotherapy drugs, but it works in synergy with most other treatments.

The great problem with chemotherapy drugs is that they do not specifically target cancer cells

The great problem with chemotherapy drugs is that they do not specifically target cancer cells in the presence of normal cells, which explains the serious toxicity problem that goes with chemotherapy for cancer patients. This means that, as in the case of IPT, very much smaller doses of the drugs can be used with DMSO-PT with little or no side effects.

Evaluation of some cancer protocols

Tragically, these developments have been violently suppressed by the authorities. it is easy to see why. Using these methods, the amount of chemo­ therapy drugs sold would be reduced by 90%, a loss of billions of dollars to the industry.

DMSO as such may be of great value in the treatment of different types of cancer. It has been shown to promote differentiation of malignant bone marrow cells, and therefore may be of value in patients who require bone marrow transplants (107).

DMSO has also been shown to retard cancer of the bladder (108), colorectal cancer (109), ovarian cancer (110), breast cancer (111) and skin cancer (112).

DMSO stimulates various parts of the immune system and scavenges hydroxyl radicals, the most dangerous of all free radicals. It also increases the flow of essential minerals across cell membranes and may diminish the effects of carcinogens by cleansing cell membranes.

Increased percentage kill of adenocarcinoma breast cancer cells by various ntineoplastic agents has been demonstrated in tissue culture in the presence of DMSO (5-10%). This was demonstrated by Dr. Pommier and associates at the University of Portland (USA). (Am J Surg1988, 155 : 672). Dramatic results on patients with various cancers by chemotherapy drugs in the presence of 10 % DMSO were subsequently shown by Hauser et al. (Ibid., p 154). More than 90% objective remissions were seen in the case of lymphoma and breast cancer patients using low-dose chemotherapy in the presence of 10% DMSO, demonstrating the effect of DMSO in vivo.

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According to Dr. Hauser et al. ( Ibid., p 153), DMSO appears to be particularly useful in the treatment of brain tumours and metastases because of the ease with which it crosses the blood-brain barrier.

Orally ingested DMSO was found to cause a twofold increase in the concentration of labelled cyclophosphamide in plasma, brain and liver tissues. The elevation persisted for about 2-3 hours, but subsequently returned to normal levels.

Similar effects are seen in humans. Typically in one experiment instead of giving 2000mg of cyclophosphamide, only 150-200mg was given per dose. This is similar to the doses used in IPT.

Remarkable results were obtained with breast cancer patients: 13 of 15 inoperable breast cancer patients with metastases were induced to remission with the DMSO-cyclophosphamide protocol. Of 65 other patients, 44 achieved remission. No side-effects were seen and pain was relieved to such an extent that no  morphine was required (Ann New York Acad Sc 1975, 243: 412). Although these promising results were obtained more than 30 years ago, no adequate follow-up studies have been conducted to confirm these very promising results due to medical scepticism and behind the scenes financial interests.

From the work done by Dr. Hauser DMSO seems to have some specific advantage.

DMSO targets cancer cells and so transports the “primary medicine” into the cancer cells. This makes the medicine more effective.

  1. DMSO has been shown to retard colorectal cancer
  2. DMSO is useful in treating metastases.
  3. Lower dosages of the “primary medicine” may be used.

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