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NAD Helpful Points

How NAD works :

Most living cells produce energy from nutrients through a process called cellular respiration.

Cellular respiration refers to the breakdown of the food we eat such as glucose and other respiratory substrates including carbohydrates, lipids and proteins) to make the energy carrying molecule ATP (Adenosine triphosphate).

For cellular respiration the extraction of energy from food molecules is what is known as oxidation. Oxidation means the removal of hydrogen, which is equal to 2 high energy electrons, from the food molecule.

The importance of NAD lies here. And acts as the transporter, or carrier of the hydrogen in this process, and exists in 2 forms, NAD+ and NADH, dependent on whether it is carrying hydrogen, or it is not. NAD+ which is the form when not carrying electrons, collects hydrogen electrons from the nutrients and food molecules we consume transforming NAD+ into NADH.

NADH then transports and donates the electrons to cells that need energy vital for life. With each of these transfers of electrons through the chemical reactions that occur, cellular energy – ATP is generated.

Once NADH has donated and no longer has its hydrogen atom, it transforms back to NAD+ and begins the cycle again. NAD is not only essential to life, it is a co-enzyme involved in energy metabolism and DNA repair and sirtuin genes are NAD dependant.

NAD levels decline with aging.

Raising NAD :

  1. Intermittent or prolonged fasting
  2. Exercise vigorously enough to create a temporary oxygen deficit (high intensity training and aerobic)
  3. Taking cold showers
  4. Saunas
  5. NAD precursors (niacin, NAD riboside, NMN). NAD itself is too big a molecule  to easily go through cell membranes)
  6. Eating parsley or drinking parsley juice (rich in apigenin) keeps an enzyme called CD38 from destroying NAD in the body.
  7. Raising NAD doesn’t do much unless we activate our sirtuin genes. There are over a dozen foods that activate sirtuins. Resveratrol from blue berries and oleic acid from olive oil are powerful sirtuin activators
  8. NAD intravenously from time to time (250-1000mg IV drips at Dr Golding’s practice)

Foods activating sirtuin genes :

The top 20 ‘sirtfoods’ : arugula, buckwheat, capers, celery, chilies, cocoa, coffee, extra virgin olive oil, garlic, green tea, kale, Medjool dates, parsley, red endive, red onion, red wine, soy, strawberries, turmeric and walnuts.

For interest Jampolis endorses the majority of this list, except for the Medjool dates (she recommends people monitoring their weight avoid dried fruit) and emphasizes the soy should be minimally processed.

Starbucks adds new Almondmilk Honey Flat White and Coconutmilk Latte to the permanent menu.

At Dr Golding’s medical practice we offer :

  • IV NAD
  • IV apigenin
  • Oral NAD riboside
  • Oral NMN/resveratrol powder mix
  • Niacin
  • Niacin and infra-red saunas
  • Thermogenesis (infra-red saunas and wellness pod)

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